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The file on cancer causing agents (RoC) is a congressionally mandated, science-based, public future health rfile that's ready for the HHS Secretary through the nationwide Toxicology Program.

The record identifies brokers, components, combinations, and publicity conditions which are recognized or kind of expected to reason melanoma in people.

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A large international casecontrol study of lung cancer found a significant smoking-adjusted risk of lung cancer with increasing acrylonitrile exposure (Scélo et al. 2004), and a meta-analysis of lung-cancer findings found increased risk with acrylonitrile exposure after adjusting for a healthy-worker effect (Sponsiello-Wang et al. 2006). A small cohort study (Czeizel et al. 2004) found no excesses of lung or other cancer among workers possibly exposed to acrylonitrile; however, the study’s statistical power to detect effects was limited.

2004), and a meta-analysis of lung-cancer findings found increased risk with acrylonitrile exposure after adjusting for a healthy-worker effect (Sponsiello-Wang et al. 2006). A small cohort study (Czeizel et al. 2004) found no excesses of lung or other cancer among workers possibly exposed to acrylonitrile; however, the study’s statistical power to detect effects was limited. In an update of a cohort study in the Netherlands, excesses of brain cancer were found in some exposure categories (Swaen et al.

J Agric Food Chem 52(7): 1996-2002. Brown L, Rhead MM, Bancroft KCC, Allen N. 1980a. Case studies of acrylamide pollution resulting from industrial use of acrylamides. Water Pollut Control 79(4): 507-510. Brown L, Rhead MM, Bancroft KCC, Allen N. 1980b. Model studies of the degradation of acrylamide monomer. Water Res 14(7): 775-778. Brown L, Rhead MM, Hill D, Bancroft KCC. 1982. Qualitative and quantitative studies on the in situ � adsorption, degradation and toxicity of acrylamide by the spiking of the waters of two sewage works and a river.

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12th Report on Carcinogens on June 10, 2011


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